The HPE ProLiant DL365 Gen11 uses registered DDR5 Smart Memory with one DIMM per channel. This reference covers the memory option kits listed for this server, the supported slot and capacity architecture, DIMM mixing restrictions, and the hardware required for higher-capacity modules.
The platform provides 12 DDR5 DIMM channels per installed processor, with 24 slots across two processors.
HPE lists seven DDR5-4800 RDIMM kits, including 128GB and 256GB 3DS modules.
128GB or 256GB memory requires performance heatsinks and seven performance fans; x4/x8 and 3DS/non-3DS mixing are prohibited.
Both processor installation and memory population determine the available capacity. One processor enables its 12 associated DIMM slots; all 24 slots require two processors.
| Specification | HPE DL365 Gen11 |
|---|---|
| Memory technology | HPE DDR5 Smart Memory, registered DIMM (RDIMM) |
| DIMM slots | 24 total, 12 per processor |
| Memory channels | 12 per processor; 1 DIMM per channel |
| Maximum system capacity | 6.0 TB with two processors and 24 x 256GB RDIMMs |
| Per-processor capacity | Up to 3 TB per processor |
| Published maximum memory data rate | 4800 MT/s at 1 DIMM per channel; actual speed depends on memory type, configuration and processor |
| Memory protection | Advanced ECC; online spare |
| Not supported | LRDIMM and persistent memory |
The motherboard provides a separate bank of 12 slots for each installed AMD EPYC processor. The manufacturer memory population diagram identifies CPU 0, CPU 1, and the front of the system.

The internal component diagram also identifies the DIMM banks and processor/heatsink locations. It shows a populated two-processor configuration, not the required population order for every configuration.

The following manufacturer-listed option kits all use DDR5-4800. Rank, DRAM device organization, latency and capacity distinguish the kits. Do not assume that DIMMs with matching speeds can be mixed.
| Part Number | Product Name | Capacity | Organization |
|---|---|---|---|
| P50309-B21 | HPE 16GB (1x16GB) Single Rank x8 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit | 16GB | Single Rank x8 |
| P50310-B21 | HPE 32GB (1x32GB) Single Rank x4 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit | 32GB | Single Rank x4 |
| P50311-B21 | HPE 32GB (1x32GB) Dual Rank x8 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit | 32GB | Dual Rank x8 |
| P50312-B21 | HPE 64GB (1x64GB) Dual Rank x4 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit | 64GB | Dual Rank x4 |
| P66676-B21 | HPE 96GB (1x96GB) Dual Rank x4 DDR5-4800 CAS-46-45-45 EC8 Registered Smart Memory Kit | 96GB | Dual Rank x4 |
The 128GB and 256GB options use 3DS registered memory. These higher-density kits have additional cooling requirements and cannot be intermixed with non-3DS DIMMs.
| Part Number | Product Name | Capacity | Organization |
|---|---|---|---|
| P50313-B21 | HPE 128GB (1x128GB) Quad Rank x4 DDR5-4800 CAS-46-39-39 EC8 Registered 3DS Smart Memory Kit | 128GB | Quad Rank x4 3DS |
| P50314-B21 | HPE 256GB (1x256GB) Octal Rank x4 DDR5-4800 CAS-46-39-39 EC8 Registered 3DS Smart Memory Kit | 256GB | Octal Rank x4 3DS |
Mixing x4 and x8 DIMMs is not allowed. The QuickSpecs also prohibits mixing 3DS and non-3DS memory. Choose a uniform and supported memory organization when planning upgrades, not just matching module speed and capacity.
Install memory only in slots belonging to installed processors. Balance DIMM capacity between processors and distribute DIMMs across both processors when two CPUs are installed. The published 6TB maximum is not attainable with a single processor.
| Configuration | Requirement or limitation |
|---|---|
| Single processor | Only the 12 DIMM slots attached to the installed processor are available |
| Two processors | Up to 24 slots available; balance DIMMs and memory capacity across CPUs |
| x4 and x8 DIMMs | Cannot be mixed |
| 3DS and non-3DS DIMMs | Cannot be mixed |
| 128GB or 256GB DIMMs | Performance heatsinks and seven performance fans are required |
| 256GB DIMMs | Additional high-profile thermal and configuration restrictions; verify build in the HPE configurator |
| Memory speed | Depends on memory type, population and processor model; DDR5-4800 describes the listed kits, not an unconditional operating speed |
| Memory blanks | Blank kit cannot be selected if all 24 DIMM slots are populated |
The QuickSpecs includes a DDR4-named blank kit in its Gen11 memory configuration section. The DDR4 designation is the manufacturer product name of the blank, not an assertion that this server supports DDR4 memory modules.
| Part Number | Product Name |
| P07818-B21 | HPE DDR4 DIMM Blank Kit |
High-density 128GB or 256GB memory selection requires performance heatsinks and seven performance fan kits. The server has separate standard and performance cooling options. These are supporting hardware references, not additional DIMM options.
| Part Number | Product Name | Role |
|---|---|---|
| P58456-B21 | HPE ProLiant DL3X5 Gen11 CPU Standard 1U Heat Sink Kit | Standard CPU heatsink |
| P58457-B21 | HPE ProLiant DL3X5 Gen11 CPU Performance 1U Heat Sink Kit | Performance CPU heatsink |
| P58461-B21 | HPE ProLiant DL3XX Gen11 1U Standard Fan Kit | Standard fan, one fan per kit |
| P58462-B21 | HPE ProLiant DL3XX Gen11 1U Performance Fan Kit | Performance fan, one fan per kit |
For systems with 128GB or 256GB DIMMs, select performance cooling rather than relying on a low-power processor configuration to qualify for standard fans. Processor wattage, drive types and chassis configuration can introduce additional restrictions beyond the memory requirements.
All three CTO chassis families have the same stated 24-slot motherboard potential, but actual memory availability depends on installed CPU count. The EDSFF CTO configuration requires two processors; the GPU chassis has separate thermal and expansion conditions.
| Part Number | Product Name |
|---|---|
| P53933-B21 | HPE ProLiant DL365 Gen11 8SFF Configure-to-order Server |
| P53934-B21 | HPE ProLiant DL365 Gen11 EDSFF Configure-to-order Server |
| P53935-B21 | HPE ProLiant DL365 Gen11 GPU Configure-to-order Server |
Before ordering memory, confirm the installed processor count, present DIMM organization, availability of the corresponding slots, and cooling kit. For a mixed-capacity or maximum-memory build, consult the HPE ProLiant Gen11 AMD EPYC 9004 memory population guidelines and use the HPE-approved configurator to validate the final bill of materials.
Documentation caution: The Standard Features section says all processors support up to 3TB memory per server, while the same section also states up to 3TB per processor and 6TB with two processors. The later two-processor capacity table and 24 x 256GB calculation support a 6TB platform maximum, but the single-server wording should be treated as inconsistent.
It uses HPE DDR5 Smart Memory registered DIMMs (RDIMMs). The listed option kits are DDR5-4800; LRDIMMs and persistent memory are not supported.
The system has 24 slots, with 12 attached to each processor. Only 12 can be populated when one CPU is installed.
The documented maximum is 6TB with two processors and 24 x 256GB RDIMMs, subject to qualification and configuration rules.
No. The QuickSpecs explicitly prohibits mixing x4 and x8 memory modules.
No. Mixing 3DS and non-3DS DIMMs is not allowed.
Selecting 128GB or 256GB memory requires performance heatsinks and seven performance fan kits. The 256GB kit has further thermal restrictions.
No. The blank kit is listed under memory accessories, but the server memory type is DDR5 RDIMM; the blank does not establish DDR4 electrical compatibility.